Second-placed City play Arsenal, managed by Guardiola's former assistant Mikel Arteta, at the Etihad on Wednesday.
Barcelona beat Girona 2-0 in a Catalan derby on Sunday to maintain their five-point lead at the top of La Liga, while Real Madrid thrashed Espanyol 4-2.
Included in Barcelona squad to face Dortmund
It was a wonder that Louis van Gaal's face did not turn as scarlet as his team's shirts.
A goal by Sergio Aguero gave Manchester City a 1-0 victory against neighbours Manchester United, who played with 10 men for more than 50 minutes on Sunday.
Argentina remain winless in South American qualifying for the 2018 World Cup after struggling to a 0-0 in Paraguay on Tuesday, while Uruguay and Ecuador both made it two wins from two games to top the group.
(Reuters) - Real Madrid, Manchester United and Paris St Germain reached the last 16 of the Champions League on Wednesday on a night when the goals flowed all over Europe with United the highest scorers in a 5-0 win at Bayer Leverkusen.
Atletico Madrid made a typically aggressive start to lay the foundations for a 2-0 victory at home.
Former Real youth player Joselu pulled a goal back for Alaves in the 59th minute, powering in a header from a free kick, but Benzema rounded off the victory for second-placed Real with an exquisite solo run and goal in the 70th minute.
Images from the English Premier League matches played at Old Trafford on Saturday
A round of Wednesday night's Champions League group stage matches.
Real Madrid kept alive their hopes of overhauling La Liga leaders Barcelona when a James Rodriguez stunner set them on their way to a serene 3-0 home victory over struggling Almeria on Wednesday.
Manchester United ushered in a new era under interim manager Ryan Giggs with a 4-0 Premier League win over Norwich City on Saturday full of the verve and attacking intent often absent under the sacked David Moyes.
Zinedine Zidane lamented Real Madrid's home woes as the Spanish and European champions slipped to a surprise 1-0 defeat to Real Betis on Wednesday.
Barcelona have emerged as favourites to be crowned champions after one defeat in their last 22 Liga games.
A round-up of Wednesday's night's UEFA Chmpions League matches.
Barcelona teenager Ansu Fati scored twice to lead his side to a 2-1 win at home to Levante on Sunday, finding the net in a league game for the first time in more than four months and becoming the youngest player to net a La Liga double. Romelu Lukaku scored a quickfire second-half double to give Inter Milan a 2-0 win at Udinese on Sunday, ending their run of three successive 1-1 league draws.
A summary of the results of the major European football league matches on the weekend.
Second division Mirandes caused an upset by knocking Deportivo La Coruna out of the King's Cup on Tuesday and Sevilla joined them in the quarter-finals after making light work of city rivals Real Betis.
News of all that's transpired on and off the football field
Morata, who had scored his first goal for the club in last week's 2-0 win over Villarreal, rose to head home from close range on the half-hour mark following a corner which had been flicked on by Atleti captain Diego Godin.
News of all that's transpired on and off the football field
Images from the Champions League matches played across Europe on Tuesday
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Karim Benzema made history at Real Madrid, the battle for the top four continues to heat up
This and more from the happenings in the world of football
Germany coach Joachim Loew has named four talented youngsters, including three uncapped players, in his preliminary 27-man squad for Euro 2016.
Spain, who have several players from their country's top two football academies - the La Masia and Real Madrid academies -- were beaten 1-2 by South American champions and hot favourites Brazil in their first Group D match.
Leicester City manager Claudio Ranieri ruled himself out of the running for the job of Italy head coach on Thursday and said he hoped to stay at the Premier League leaders for years to come.
A summary of Sunday's action in Serie A and Bundesliga.
Newcastle grabbed a point to leave City manager Pep Guardiola frustrated.
Atletico Madrid knocked Barcelona off the top of La Liga, for a day at least, as a second-half strike by Koke earned a 1-0 victory over a stubborn Malaga side on Saturday.
Jose Mourinho's Chelsea turned from domestic whipping boys back to European stalwarts on Wednesday, beating his former club Porto 2-0 to top Champions League Group G.
This and more from the happenings in the world of football
Images from the football matches played across Europe on Sunday.
News of all that's transpired on and off the football field
Leaders Chelsea stretched their Premier League winning run to a club record-equalling 11 as Diego Costa's header shortly before halftime secured a 1-0 victory at London rivals Crystal Palace on Saturday.
Lionel Messi marked his 300th La Liga appearance with a record-equalling hat-trick and an assist for Neymar as Barcelona stayed hard on the heels of leaders Real Madrid with a 5-0 romp at home to Levante on Sunday.
Summary of sports events and persons who made news on Friday
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